5,10-Methylenetetrahydrofolate, Thymidylate synthase (FAD), 3-methyl-2-oxobutanoate hydroxymethyltransferase

5,10-Methylenetetrahydrofolate: 5,10-Methylenetetrahydrofolate ( N5, N10-Methylenetetrahydrofolate; 5,10-CH 2 -THF ) he cofactor i loko o kekahi mau hopena biochemical. Aia i loko o ke kūlohelohe e like me ka diastereoisomer [6R] -5,10-methylene-THF.
Thymidylate synthase (FAD): I ka enzymology, kahi thymidylate synthase ( FAD ) (EC 2.1.1.148 ) kahi enzyme e catalyze i ka hopena kemika 5,10-methylenetetrahydrofolate + dUMP + FADH 2 dTMP + tetrahydrofolate + FAD
3-methyl-2-oxobutanoate hydroxymethyltransferase: I loko o ka enzymology, he 3-methyl-2-oxobutanoate hydroxymethyltransferase (EC 2.1.2.11 ) kahi enzyme e catalyzed i ka hopena kemika 5,10-methylenetetrahydrofolate + 3-methyl-2-oxobutanoate + H 2 O tetrahydrofolate + 2-dehydropantoate
D-alanine 2-hydroxymethyltransferase: I loko o ka enzymology, kahi D-alanine 2-hydroxymethyltransferase (EC 2.1.2.7 ) kahi enzyme e catalyzed i ka hopena kemika 5,10-methylenetetrahydrofolate + D-alanine + H 2 O. tetrahydrofolate + 2-methylserine
Methylenetetrahydrofolate dehydrogenase (NAD +): I ka enzymology, kahi methylenetetrahydrofolate dehydrogenase (NAD + ) (EC 1.5.1.15 ) kahi enzyme e catalyzed i kahi hopena kemika. 5,10-methylenetetrahydrofolate + NAD + 5,10-methenyltetrahydrofolate + NADH + H +
Methylenetetrahydrofolate dehydrogenase (NADP +): I ka enzymology, kahi methylenetetrahydrofolate dehydrogenase (NADP +) (EC 1.5.1.5 ) kahi enzyme e catalyzed i ka hopena kemika 5,10-methylenetetrahydrofolate + NADP + 5,10-methenyltetrahydrofolate + NADPH + H +
Deoxycytidylate C-methyltransferase: I ka enzymology, he deoxycytidylate C-methyltransferase kahi ʻākena e catalyzed i ka hopena kemika 5,10-methylenetetrahydrofolate + dCMP dihydrofolate + deoxy-5-methylcytidylate
ʻO thymidylate synthase: ʻO ka thymidylate synthase (TS) kahi enzyme e catalysy i ka hoʻololi ʻana o deoxyuridine monophospate (dUMP) i deoxythymidine monophosphate (dTMP). ʻO Thymidine kekahi o nā nucleotides ma DNA. Me ka pāpā o TS, kū mai kahi kaulike ʻole o deoxynucleotides a hoʻonui ʻia nā pae o DUMP. Hana lāua ʻelua i ka hōʻino ʻia o DNA.
ʻO Deoxycytidylate 5-hydroxymethyltransferase: I ka enzymology, he deoxycytidylate 5-hydroxymethyltransferase (EC 2.1.2.8 ) kahi enzyme e catalyzed i ka hopena kemika 5,10-methylenetetrahydrofolate + H 2 O + deoxycytidylate tetrahydrofolate + 5-hydroxymethyldeoxycytidylate
Serine hydroxymethyltransferase: ʻO Serine hydroxymethyltransferase (SHMT) kahi pyridoxal phosphate (PLP) (Vitamin B 6 ) ka enzyme hilinaʻi (EC 2.1.2.1 ) e hana nui i nā ala kalapona hoʻokahi-kalapona e ka catalyzing i ka hoʻohuli hou ʻia, ka hoʻololi like ʻana o L-serine i glycine a tetrahydrofolate (THF) i 5,10-Methylenetetrahydrofolate (5,10-CH 2 -THF). Hāʻawi kēia hopena i ka ʻāpana nui loa o nā anakahi kalapona i loaʻa i ka pūnaewele.
Methylenetetrahydrofolate — tRNA- (uracil-5 -) - methyltransferase: I ka enzymology, kahi methylenetetrahydrofolate-tRNA- (uracil-5 -) - methyltransferase (EC 2.1.1.74 ) kahi enzyme e catalyzed i ka hopena kemika 5,10-methylenetetrahydrofolate + tRNA i loaʻa ka uridine ma ke kūlana 54 + FADH 2 tetrahydrofolate + tRNA i loaʻa ribothymidine ma ke kūlana 54 + FAD
Methylenetetrahydromethanopterin dehydrogenase: I ka enzymology, he methylenetetrahydromethanopterin dehydrogenase (EC 1.5.98.1 ) kahi enzyme e catalyze i ka hopena kemika 5,10-methylenetetrahydromethanopterin + coenzyme F 420 5,10-methenyltetrahydromethanopterin + hoʻoliʻiliʻi coenzyme F 420
5,10-methylenetetrahydromethanopterin reductase: I loko o ka enzymology, kahi 5,10-methylenetetrahydromethanopterin reductase (EC 1.5.99.11 ) kahi enzyme e catalyzed i ka hopena kemika 5-methyltetrahydromethanopterin + coenzyme F 420 5,10-methylenetetrahydromethanopterin + hoʻoliʻiliʻi coenzyme F 420
5,12-Bis (phenylethynyl) naphthacene: 5,12-Bis (phenylethynyl) naphthacene kahi pena fluorescent i hoʻohana ʻia i nā kukui uila. Hāʻawi ia i ke kukui ʻalani.
5,12-Bis (phenylethynyl) naphthacene: 5,12-Bis (phenylethynyl) naphthacene kahi pena fluorescent i hoʻohana ʻia i nā kukui uila. Hāʻawi ia i ke kukui ʻalani.
5,12-Bis (phenylethynyl) naphthacene: 5,12-Bis (phenylethynyl) naphthacene kahi pena fluorescent i hoʻohana ʻia i nā kukui uila. Hāʻawi ia i ke kukui ʻalani.
Xanthommatin hōʻemi: I ka enzymology, kahi xanthommatin reductase (EC 1.3.1.41 ) kahi enzyme e catalyzed i ka hopena kemika 5,12-dihydroxanthommatin + NAD + xanthommatin + NADH + H +
Androstadienol: ʻO Androstadienol , a i ʻole androsta-5,16-dien-3β-ol , kahi steroid endogenous, pheromone, a me waena waena o nā kemika i loaʻa i ka hou o nā kāne a me nā wahine.
Androstadienol: ʻO Androstadienol , a i ʻole androsta-5,16-dien-3β-ol , kahi steroid endogenous, pheromone, a me waena waena o nā kemika i loaʻa i ka hou o nā kāne a me nā wahine.
Millennium BC: ʻO ka millennium BC BC i kuhi aku i nā makahiki 6000 BC a hiki i 5001 BC. ʻAʻole hiki ke kikoʻī i nā hanana i hiki mai a puni ka manawa o kēia milenio a ʻo nā lā āpau i ʻōlelo ʻia ma aneʻi, he kuhi ka hapanui ma muli o ka hoʻokolohua kālaihonua a me ka anthropological. Heluhelu ʻia kēia milenio e hōʻailona i ka hopena o ka deglaciation honua i ukali i ka Last Glacial Maximum a piʻi aʻe ke kai e kahi 60 m (200 ft) ma kahi o 5,000 mau makahiki.
5,271,009: ʻO "5,271,009" kahi moʻolelo ʻepekema / moemoeā na ka mea kākau ʻAmelika ʻo Alfred Bester. ʻO ka mea i paʻi ʻia ma The Magazine of Fantasy & Science Fiction , i ka 1954, ʻike ʻia ʻo ia ʻo "The Starcomber" .
Rhamnazin: ʻO Rhamnazin kahi flavonol O -methylated , kahi ʻano o ka hui kemika. Hiki ke loaʻa iā ia ma Rhamnus petiolaris , kahi lāʻau buckthorn mea kanu i Sri Lanka.
Ayanin: ʻO Ayanin kahi flavonol O -methylated , kahi ʻano flavonoid. ʻO ia ka 3,7,4'-tri- O -methylated derivative o quercetin.
120-ʻea: I ke geometry, ʻo ka 120-cell ka convex mau 4-polytope me Schläfli hōʻailona {5,3,3}. Kāhea ʻia kekahi C 120 , dodecaplex (pōkole no "dodecahedral complex"), hyperdodecahedron , polydodecahedron , hecatonicosachoron , dodecacontachoron a me hecatonicosahedroid .
Hoʻonohonoho manawa a me nā ʻūpili mālama: I ka ʻepekema lolouila, ʻo ka hoʻoliʻiliʻi manawa a me nā ʻūpili waiho pūnaewele kahi papa o nā pilikia lako polokalamu i hiki ai ke mālama pono ʻole i ka helu a me ka helu. ʻO kēia nā hōʻike pinepine o ka kahe ana o ka helu, akā hiki ke hopena i nā pilikia ʻē aʻe. ʻO ka hopena i ʻike nui ʻia o nā puʻupuʻu o kēia ʻano ka pilikia Y2K, akā nui nā lā milestone ʻē aʻe a i ʻole nā ​​manawa i kū i kumu a i ʻole nā ​​pilikia e pili ana i nā hemahema o ka papahana.
Europinidin: ʻO Europinidin (Eu) kahi anthocyanidin O-methylated. He wai hiki ke hoʻoheheʻe ʻia i ka wai, a me ka waihoʻoluʻu ʻulaʻula bluish. He O-methylated flavonoid kākaʻikahi, kahi mea i loaʻa i ka delphinidin. Hiki ke loaʻa ma kekahi ʻano o Plumbago a me Ceratostigma .
ʻO Genkwanin: ʻO Genkwanin kahi flavoneid O-methylated, kahi ʻano flavonoid. Hiki ke loaʻa i nā ʻanoʻano o Alnus glutinosa , a me nā lau o ka ferns Notholaena bryopoda a me Asplenium normale a me Aquilaria .
Kumatakenin: ʻO Kumatakenin kahi flavonol O-methylated. Hiki ke loaʻa ma Astragalus membranaceus .
Prunetin: ʻO Prunetin kahi O-methylated isoflavone, kahi ʻano flavonoid. Ua hoʻokaʻawale ʻia ia no ka manawa mua e Finnemore ma 1910 i ka ʻā o Prunus emarginata . ʻO Prunetin kaawale mai nā aʻa pea hiki ke hana ma ke ʻano he mea hoʻohihi no Aphanomyces euteiches zoospores. ʻO ia kahi mea kāohi allosteric o ke kanaka aldehyde dehydrogenase.
Blue Cadet-3, Hoʻohui ʻoe ?: Blue Cadet-3, Hoʻohui ʻoe? ʻO ka hoʻokuʻu mua EP o Modest Mouse. Ua hoʻokuʻu ʻia e K Records i ka makahiki 1994. Ma kahi o 300 mau kope i kaomi mua ʻia. Loaʻa nā ala āpau o kēia hoʻokuʻu ma kā lākou hoʻokuʻu 2001 S Sad Sappy Sucker .
ʻO Dimedone: ʻO Dimedone kahi diketone cyclic i hoʻohana ʻia i ka kemika kemika e hoʻoholo ai inā loaʻa kahi hui aldehyde i kahi hui. Hiki ke hoʻohana ʻia ʻo Cyclohexanediones ma ke ʻano he catalysts i ka hoʻokumu ʻia ʻana o nā complex-metal complex. ʻO nā hoʻohana ʻē aʻe e pili ana i nā noi i ka colorimetry, crystallography, luminescence a me ka aniani spectrophotometric. Hiki ke hoʻohana ʻia no ke kemika e pili ana i nā mea kūpona o ke kūpaʻa uila haʻahaʻa.
Magnolol: ʻO Magnolol kahi hui kūmole i hoʻonohonoho ʻia ma ke ʻano he lignan. He hui bioactive ia i loaʻa i ka ʻili o ka Houpu magnolia a i ʻole ma M. grandiflora . Aia ka pūhui ma ka pae o kekahi mau pākēneka i ka ʻili o nā ʻano o magnolia, nā mea i hoʻohana ʻia i hoʻohana ʻia i ka lāʻau kuʻuna Kina a me Iapana. Ma waho aʻe o ka magnolol, pili nā lignans e pili ana me nā honokiol, kahi isomer o magnolol.
Magnolol: ʻO Magnolol kahi hui kūmole i hoʻonohonoho ʻia ma ke ʻano he lignan. He hui bioactive ia i loaʻa i ka ʻili o ka Houpu magnolia a i ʻole ma M. grandiflora . Aia ka pūhui ma ka pae o kekahi mau pākēneka i ka ʻili o nā ʻano o magnolia, nā mea i hoʻohana ʻia i hoʻohana ʻia i ka lāʻau kuʻuna Kina a me Iapana. Ma waho aʻe o ka magnolol, pili nā lignans e pili ana me nā honokiol, kahi isomer o magnolol.
ʻO Indigo carmine: ʻO ka Indigo carmine , a i ʻole 5,5′-indigodisulfonic acid paʻakai paʻakai , he paʻakai paʻakai i loaʻa mai i ka indigo e ka sulfonation ʻaʻala, kahi e hoʻoheheʻe ʻia ai ka hui i ka wai. Ua ʻae ʻia no ka hoʻohana ʻana i ka waihoʻoluʻu meaʻai i ka US a me EU Loaʻa iā ia ka helu E E132 . He hōʻailona PH kekahi ia.
ʻO Dimedone: ʻO Dimedone kahi diketone cyclic i hoʻohana ʻia i ka kemika kemika e hoʻoholo ai inā loaʻa kahi hui aldehyde i kahi hui. Hiki ke hoʻohana ʻia ʻo Cyclohexanediones ma ke ʻano he catalysts i ka hoʻokumu ʻia ʻana o nā complex-metal complex. ʻO nā hoʻohana ʻē aʻe e pili ana i nā noi i ka colorimetry, crystallography, luminescence a me ka aniani spectrophotometric. Hiki ke hoʻohana ʻia no ke kemika e pili ana i nā mea kūpona o ke kūpaʻa uila haʻahaʻa.
Hydantoin: ʻO Hydantoin , a i ʻole glycolylurea , kahi hui kūlohelohe heterocyclic me ke ʻano CH 2 C (O) NHC (O) NH. He paʻa kala ʻole ia e ala aʻe mai ka hopena o ka acid glycolic a me ka urea. He mea loaʻa oxidized o imidazolidine. Ma ke ʻano laulā, hiki i nā hydantoins ke kuhikuhi i nā hui a me ka papa o nā pūhui me ke kinikini like me ka makua. ʻO kahi laʻana, phenytoin (i ʻōlelo ʻia ma lalo) he ʻelua mau hui phenyl i pani ʻia i ka helu 5 kalapona i kahi mole Hydantoin.
Millennium BC: ʻO ka millennium BC BC i kuhi aku i nā makahiki 6000 BC a hiki i 5001 BC. ʻAʻole hiki ke kikoʻī i nā hanana i hiki mai a puni ka manawa o kēia milenio a ʻo nā lā āpau i ʻōlelo ʻia ma aneʻi, he kuhi ka hapanui ma muli o ka hoʻokolohua kālaihonua a me ka anthropological. Heluhelu ʻia kēia milenio e hōʻailona i ka hopena o ka deglaciation honua i ukali i ka Last Glacial Maximum a piʻi aʻe ke kai e kahi 60 m (200 ft) ma kahi o 5,000 mau makahiki.
Rubrene: ʻO Rubrene ( 5,6,11,12-tetraphenyltetracene ) he waiʻula polika uila ʻulaʻula kala. Hoʻohana ʻia ʻo Rubrene ma ke ʻano he sensitiser i ka chemoluminescence a ma ke ʻano he kukui melemele i nā kukui.
Rubrene: ʻO Rubrene ( 5,6,11,12-tetraphenyltetracene ) he waiʻula polika uila ʻulaʻula kala. Hoʻohana ʻia ʻo Rubrene ma ke ʻano he sensitiser i ka chemoluminescence a ma ke ʻano he kukui melemele i nā kukui.
Rubrene: ʻO Rubrene ( 5,6,11,12-tetraphenyltetracene ) he waiʻula polika uila ʻulaʻula kala. Hoʻohana ʻia ʻo Rubrene ma ke ʻano he sensitiser i ka chemoluminescence a ma ke ʻano he kukui melemele i nā kukui.
Rubrene: ʻO Rubrene ( 5,6,11,12-tetraphenyltetracene ) he waiʻula polika uila ʻulaʻula kala. Hoʻohana ʻia ʻo Rubrene ma ke ʻano he sensitiser i ka chemoluminescence a ma ke ʻano he kukui melemele i nā kukui.
ʻO Scutellarein: ʻO Scutellarein kahi flavone i hiki ke loaʻa ma Scutellaria lateriflora a me nā lālā ʻē aʻe o ka genus Scutellaria , a me ka fern Asplenium belangeri .
5,6,7,8: ʻO " 5,6,7,8 " kahi mele na ka hui Pelekane Steps mai kā lākou album studio studio, Step One (1998). He mele techno-pop i kākau ʻia ʻo Barry Upton lāua ʻo Steve Crosby, a hana ʻia e Karl Twigg, Mark Topham a me Pete Waterman. Ua hoʻokuʻu ʻia e like me kā lākou mele mua i Nowemapa 1997 ma hope o ko lākou hui pū ʻana ma hope o ka pane ʻana o kēlā me kēia lālā o ka hui i kahi hoʻolaha makasina e ʻimi nei i ka poʻe e hoʻolohe i ka pop band. Ua loaʻa iā ia kahi loiloi maikaʻi ʻole mai Peter Robinson o NME a piʻi i ka helu 14 ma ka UK Singles Chart — kekahi o ko lākou kūlana haʻahaʻa - akā ua lilo i ke kolu o nā mea kūʻai aku maikaʻi loa o kā lākou ʻoihana ma United Kingdom, ke kūʻai aku nei i nā kope he 365,000 a loaʻa 3,440,000 mau kahawai a hiki i Malaki 2017. Ua piʻi aʻe ka "5,6,7,8" ma ka helu ʻekahi ma ʻAukekulia a hōʻea i ka ʻelima kiʻekiʻe ma Belgika a me Nūhōlani. Ua kī ʻia kāna wikiō mele ma kahakai a hōʻike i ka hui e hoʻokele nei i nā paikikala a me ka hulahula ʻana i ka pā. Ua hoʻokō ʻia ʻo "5,6,7,8" ma The Ultimate Tour ma 2012 a me ka ʻaoʻao ma ka Dancefloor Tour ma 2017.
Nā 5.6.7.8's: ʻO ka 5.6.7.8's kahi trio pōhaku hale kaʻa Kepani mai Tokyo. Ua hoʻomaka mua lākou i ka hana ma ke ʻano he quartet ma Tokyo, a ua hōʻuluʻulu i nā mea hoʻokipa hoʻokipa ma kā lākou huakaʻi Australia. Ua lilo lākou i ʻekolu i ka makahiki 1992, ma mua o ka huakaʻi ʻana iā Australia.
ʻO Tetrahydrobiopterin: ʻO Tetrahydrobiopterin ( BH 4 , THB ), ʻike ʻia ʻo sapropterin (INN), kahi cofactor o nā ʻākena amino acid hydroxylase ʻekolu i hoʻohana ʻia, i hoʻohana ʻia i ka hoʻohaʻahaʻa o ka amino acid phenylalanine a me ka biosynthesis o nā neurotransmitters serotonin (5-hydroxytr Egyptamine, 5 -HT), melatonin, dopamine, norepinephrine (noradrenaline), epinephrine (adrenaline), a he cofactor no ka hana ʻana o nitric oxide (NO) e nā syntheses nitric oxide. ʻO Chemically, ʻo kāna ʻano o kahi (dihydropteridine reductase) hoʻemi i ka pteridine derivative (Quinonoid dihydrobiopterin).
ʻO Pteridine reductase: I ka enzymology, kahi pteridine reductase (EC 1.5.1.33 ) kahi enzyme e catalyzed i ka hopena kemika 5,6,7,8-tetrahydrobiopterin + 2 NADP + biopterin + 2 NADPH + 2 H +
Tetrahydrofolicʻakika: ʻO Tetrahydrofolic acid ( THFA ), a i ʻole tetrahydrofolate , kahi mea loaʻa mai folic acid.
Dihydrofolate hōʻemi: ʻO Dihydrofolate reductase , a i ʻole DHFR , kahi enzyme e hoʻemi ana i ka waikawa dihydrofolic i tetrahydrofolic acid, me ka hoʻohana ʻana i ka NADPH ma ke ʻano he mea hāʻawi uila, i hiki ke hoʻololi ʻia i nā ʻano tetrahydrofolate cofactors i hoʻohana ʻia i loko o ka kemika hoʻoili 1-kalapona. I ke kanaka, hoʻopā'ālua ʻia ka ʻenekia DHFR e ka ʻāpana DHFR . Loaʻa ia i ka ʻāpana q11 → q22 o ka chromosome 5. Loaʻa i nā ʻano koʻohune nā ʻelima DHFR ʻokoʻa, akā like like nā DHFR mammalian.
6,7-dihydropteridine hōʻemi: I ka enzymology, he 6,7-dihydropteridine reductase (EC 1.5.1.34 , a ʻo Dihydrobiopterin reductase ) kekahi ʻākena e catalyzed i ka hopena kemika 5,6,7,8-tetrahydropteridine + NAD (P) + 6,7-dihydropteridine + NAD (P) H + H +
Nā anuu (pūʻulu pop): ʻO nā ʻanuʻu he hui hula-pop Pelekane e komo pū ana me Lee Latchford-Evans, Claire Richards, Lisa Scott-Lee, Faye Tozer a me Ian "H" Watkins. Ua hoʻokumu ʻia nā ʻanuʻu i ka Mei 1997 e Tim Byrne, Barry Upton a me Steve Crosby a ua hoʻokuʻu ʻia he ʻeono mau album studio, ʻekolu mau album compilation a me 23 mau single. He kani kanikani pop-ko kā lākou mele. Hoʻokumu ʻia ko lākou inoa i kahi kahua kūʻai: ʻo kēlā me kēia o kā lākou mau wikiō mele e choreographed, a ua hoʻokomo ʻia nā ʻanuʻu hulahula i ka lima me ka hapa nui o kā lākou mau mele.
5,6,7,8: ʻO " 5,6,7,8 " kahi mele na ka hui Pelekane Steps mai kā lākou album studio studio, Step One (1998). He mele techno-pop i kākau ʻia ʻo Barry Upton lāua ʻo Steve Crosby, a hana ʻia e Karl Twigg, Mark Topham a me Pete Waterman. Ua hoʻokuʻu ʻia e like me kā lākou mele mua i Nowemapa 1997 ma hope o ko lākou hui pū ʻana ma hope o ka pane ʻana o kēlā me kēia lālā o ka hui i kahi hoʻolaha makasina e ʻimi nei i ka poʻe e hoʻolohe i ka pop band. Ua loaʻa iā ia kahi loiloi maikaʻi ʻole mai Peter Robinson o NME a piʻi i ka helu 14 ma ka UK Singles Chart — kekahi o ko lākou kūlana haʻahaʻa - akā ua lilo i ke kolu o nā mea kūʻai aku maikaʻi loa o kā lākou ʻoihana ma United Kingdom, ke kūʻai aku nei i nā kope he 365,000 a loaʻa 3,440,000 mau kahawai a hiki i Malaki 2017. Ua piʻi aʻe ka "5,6,7,8" ma ka helu ʻekahi ma ʻAukekulia a hōʻea i ka ʻelima kiʻekiʻe ma Belgika a me Nūhōlani. Ua kī ʻia kāna wikiō mele ma kahakai a hōʻike i ka hui e hoʻokele nei i nā paikikala a me ka hulahula ʻana i ka pā. Ua hoʻokō ʻia ʻo "5,6,7,8" ma The Ultimate Tour ma 2012 a me ka ʻaoʻao ma ka Dancefloor Tour ma 2017.
Nā 5.6.7.8's: ʻO ka 5.6.7.8's kahi trio pōhaku hale kaʻa Kepani mai Tokyo. Ua hoʻomaka mua lākou i ka hana ma ke ʻano he quartet ma Tokyo, a ua hōʻuluʻulu i nā mea hoʻokipa hoʻokipa ma kā lākou huakaʻi Australia. Ua lilo lākou i ʻekolu i ka makahiki 1992, ma mua o ka huakaʻi ʻana iā Australia.
Baicalein: ʻO Baicalein (5,6,7-trihydroxyflavone) kahi flavone, kahi ʻano flavonoid, hoʻokaʻawale mua ʻia mai nā aʻa o Scutellaria baicalensis a me Scutellaria lateriflora . Hōʻike pū ʻia ia ma Oroxylum nunjukkeun a me Tyme . ʻO ia ka aglycone o baicalin. ʻO Baicalein kekahi o nā mea hana o Sho-Saiko-To, kahi mea kanu lāʻau Kina i manaʻo ʻia e hoʻonui i ke olakino ate.
ʻO ka hui koko B laina kaulahao alpha-1,3-galactosidase: ʻO Baicalin-beta-D-glucuronidase (EC 3.2.1.167 , baicalinase ) kahi enzyme me ka inoa ʻōnaehana 5,6,7-trihydroxyflavone-7-O-beta-D-glucupyranosiduronate glucuronosylhydrolase . Hoʻopili kēia enzyme i ka hopena kemika i lalo baicalin + H 2 ʻO baicalein + D-glucuronate
ʻO Beta-Naphthoflavone: ʻO beta -Naphthoflavone , i ʻike ʻia he 5,6-benzoflavone , kahi agonist ikaika o ka aryl hydrocarbon receptor a ʻoiai he mea hoʻokomo i nā enzyme detoxification e like me cytochromes P450 (CYPs) a me uridine 5'-diphospho-glucuronosyltransferases (UGTs). ʻO β-Naphthoflavone kahi agena chemopreventive putative.
Dehydroepiandrolone: ʻO Dehydroepiandrolone ( DHEA ), ʻike ʻia ʻo androstenolone , kahi endogenous steroid pūnana mua. ʻO ia kekahi o nā steroid e hoʻopuni nei i nā kānaka. Hana ʻia ka DHEA ma nā gland adrenal, nā gonad, a me ka lolo. Hana ia ma ke ʻano he metabolic intermediate i ka biosynthesis o ka androgen a me ka estrogen sex steroid i loko o nā gonad a me nā kino like ʻole. Eia nō naʻe, he ʻano like ʻole kā DHEA o nā hopena biological i loko o kāna pono ponoʻī, e hoʻopaʻa ana i nā lālani o nā ʻenekini nuklea a me nā ʻili pūnaewele, a ke hana nei ma ke ʻano he neurosteroid a me ka modulator o nā mea loaʻa nā neurotrophic factor.
Dehydroepiandrolone: ʻO Dehydroepiandrolone ( DHEA ), ʻike ʻia ʻo androstenolone , kahi endogenous steroid pūnana mua. ʻO ia kekahi o nā steroid e hoʻopuni nei i nā kānaka. Hana ʻia ka DHEA ma nā gland adrenal, nā gonad, a me ka lolo. Hana ia ma ke ʻano he metabolic intermediate i ka biosynthesis o ka androgen a me ka estrogen sex steroid i loko o nā gonad a me nā kino like ʻole. Eia nō naʻe, he ʻano like ʻole kā DHEA o nā hopena biological i loko o kāna pono ponoʻī, e hoʻopaʻa ana i nā lālani o nā ʻenekini nuklea a me nā ʻili pūnaewele, a ke hana nei ma ke ʻano he neurosteroid a me ka modulator o nā mea loaʻa nā neurotrophic factor.
Dehydronorketamine: ʻO Dehydronorketamine ( DHNK ), a i ʻole 5,6-dehydronorketamine , kahi metabolite liʻiliʻi o ka ketamine i hana ʻia e ka dehydrogenation o kāna metabolite norketamine. ʻOiai manaʻo mua ʻole ʻia e hana ʻole, ua ʻike ʻia ka DHNK e hana ma ke ʻano he modulator allosteric maikaʻi a koho ʻia o ka α 7 -nicotinic acetylcholine receptor ( IC 50 = 55 nM). No kēia kumu, like me ka hydroxynorketamine (HNK), ua kuhi ʻia he mana ko DHNK e hana i nā hopena antidepressant wikiwiki. Eia nō naʻe, ʻokoʻa ka ketamine, norketamine, a me HNK, ʻike ʻole ʻia ka hana ʻole o DHNK i ka hōʻike ʻauʻau ʻauʻau (FST) i nā ʻiole ma nā kaha a i 50 mg / kg. Hana ʻole ʻo DHNK ma ka receptor α 3 β 4 -nicotinic acetylcholine (IC 50 > 100 μM) a hana palupalu wale i ka receptor NMDA (K i = 38.95 μM no ( S ) - (+) - DHNK). Hiki ke ʻike ʻia he 7-10 mau lā ma hope o kahi mahele haʻahaʻa o ka ketamine, a ma muli o kēia, pono i nā hoʻokolohua ʻike lāʻau.
5,6-Dichloro-1-beta-D-ribofuranosylbenzimidazole: 5,6-Dichloro-1-β- d -ribofuranosylbenzimidazole (DRB) kahi hui kemika e kāohi i ka elongation transcription na RNA Polymerase II. Pili ka ʻike i ka DRB ma muli o ka DRB ʻike ʻia i ke kumu (DSIF), ke kumu elongation maikaʻi (NELF), a me ka helu elongation transcription maikaʻi b (P-TEFb). ʻO DRB kahi analog nukleoside a pāpā pū kekahi i kekahi kinases protein.
Dehydroepiandrolone: ʻO Dehydroepiandrolone ( DHEA ), ʻike ʻia ʻo androstenolone , kahi endogenous steroid pūnana mua. ʻO ia kekahi o nā steroid e hoʻopuni nei i nā kānaka. Hana ʻia ka DHEA ma nā gland adrenal, nā gonad, a me ka lolo. Hana ia ma ke ʻano he metabolic intermediate i ka biosynthesis o ka androgen a me ka estrogen sex steroid i loko o nā gonad a me nā kino like ʻole. Eia nō naʻe, he ʻano like ʻole kā DHEA o nā hopena biological i loko o kāna pono ponoʻī, e hoʻopaʻa ana i nā lālani o nā ʻenekini nuklea a me nā ʻili pūnaewele, a ke hana nei ma ke ʻano he neurosteroid a me ka modulator o nā mea loaʻa nā neurotrophic factor.
5,6-Dihydro-5 (α-thyminyl) thymine: ʻO 5,6-Dihydro-5 (α-thyminyl) koumine kahi DNA pyrimidine dimer photoproduct i hana ʻia ke hōʻike ʻia ʻo DNA i nā spore bacteria i ke kukui ultraviolet.
ʻO Dihydrouracil: ʻO Dihydrouracil kahi mea waena i ka catabolism o uracil.
5,6-Dihydroxycytosine: 5,6-Dihydroxycytosine hiki ke hana ʻia mai ka mālama ʻana iā DNA me ka osmium tetroxide.
5,6-MDO-DMT: 5,6-MDO-DMT , a i ʻole 5,6-methylenedioxy- N , N -dimethyltr Egyptamine , kahi lāʻau psychedelic kaulana ʻole i ʻike ʻia. ʻO ia ka analog 5,6-methylenedioxy o DMT. 5,6-MDO-DMT i hana mua ʻia e Alexander Shulgin. I loko o kāna puke TiHKAL , he 5,6-MDO-DMT i hana i nā hopena psychoactive i ʻike ʻole ʻia, ʻoiai ua hoʻāʻo wale ʻia a hiki i kahi lāʻau o 5 mg. Aia nā ʻikepili liʻiliʻi loa e pili ana i nā waiwai lāʻau, metabolism, a me nā mea make o 5,6-MDO-DMT.
5,6-MDO-DiPT: 5,6-MDO-DiPT , a i ʻole 5,6-methylenedioxy- N , N -diisopropyltr Egyptamine , kahi lāʻau psychedelic kaulana ʻole i ʻike ʻia. ʻO ia ka analog 5,6-methylenedioxy o DiPT. ʻO 5,6-MDO-DiPT i synthesize mua ʻia e Alexander Shulgin. Ua ʻōlelo ʻia i loko o kāna puke TiHKAL , akā ʻaʻole i hoʻāʻo ʻia he 5,6-MDO-DiPT e hoʻoholo ai i nā hopena e hana ai, inā he. Aia nā ʻikepili liʻiliʻi loa e pili ana i nā pono lāʻau, ka metabolism, a me ka ʻawahia o 5,6-MDO-DiPT.
5,6-MDO-MiPT: ʻO 5,6-MDO-MiPT , a i ʻole 5,6-methylenedioxy-N-methyl-N-isopropyltr Egyptamine , kahi lāʻau psychedelic i ʻike ʻole ʻia. ʻO ia ka analog 5,6-methylenedioxy o MiPT. 5,6-MDO-MiPT i synthesize mua ʻia e Alexander Shulgin. I loko o kāna puke TiHKAL , hana ʻo 5,6-MDO-MiPT i kahi paresthesia liʻiliʻi ma nā kaha haʻahaʻa. Aia nā ʻikepili liʻiliʻi loa e pili ana i nā pono lāʻau, nā metabolism, a me nā mea ʻino o 5,6-MDO-MiPT.
5,6-MeO-MiPT: ʻO 5,6-MeO-MiPT , a i ʻole 5,6-dimethoxy-N-methyl-N-isopropyltr Egyptamine , kahi lāʻau psychedelic i ʻike liʻiliʻi ʻia. ʻO ia ka 5,6-dimethoxy analog o MiPT. 5,6-MeO-MiPT i synthesize mua ʻia e Alexander Shulgin. I loko o kāna puke TiHKAL , he 5,6-MeO-MiPT i hana i nā hopena psychoactive i ʻike ʻole ʻia. Aia nā ʻikepili liʻiliʻi loa e pili ana i nā waiwai lāʻau, metabolism, a me nā mea make o 5,6-MeO-MiPT.
MDAI: ʻO MDAI ( 5,6-methylenedioxy-2-aminoindane ) kahi lāʻau i hoʻomohala ʻia i nā makahiki 1990 e kahi kime i alakaʻi ʻia e David E. Nichols ma ke Kulanui ʻo Purdue. Hana ia ma ke ʻano he neurotoxic non-selective a me ke koho koho serotonin (SSRA) i vitro a hana i nā hopena entactogen i nā kānaka.
MDAI: ʻO MDAI ( 5,6-methylenedioxy-2-aminoindane ) kahi lāʻau i hoʻomohala ʻia i nā makahiki 1990 e kahi kime i alakaʻi ʻia e David E. Nichols ma ke Kulanui ʻo Purdue. Hana ia ma ke ʻano he neurotoxic non-selective a me ke koho koho serotonin (SSRA) i vitro a hana i nā hopena entactogen i nā kānaka.
MDMAI: 5,6-Methylenedioxy- N -methyl-2-aminoindane ( MDMAI ), he lāʻau i hoʻomohala ʻia i nā makahiki 1990 e kahi hui i alakaʻi ʻia e David E. Nichols ma ke Kulanui ʻo Purdue. Hana ia ma ke ʻano neurotrokika non-neurotoxic a me ka mea koho nui loa (SSRA) i nā holoholona a me kahi entactogen putative i loko o nā kānaka.
MDMAI: 5,6-Methylenedioxy- N -methyl-2-aminoindane ( MDMAI ), he lāʻau i hoʻomohala ʻia i nā makahiki 1990 e kahi hui i alakaʻi ʻia e David E. Nichols ma ke Kulanui ʻo Purdue. Hana ia ma ke ʻano neurotrokika non-neurotoxic a me ka mea koho nui loa (SSRA) i nā holoholona a me kahi entactogen putative i loko o nā kānaka.
ʻO Beta-Naphthoflavone: ʻO beta -Naphthoflavone , i ʻike ʻia he 5,6-benzoflavone , kahi agonist ikaika o ka aryl hydrocarbon receptor a ʻoiai he mea hoʻokomo i nā enzyme detoxification e like me cytochromes P450 (CYPs) a me uridine 5'-diphospho-glucuronosyltransferases (UGTs). ʻO β-Naphthoflavone kahi agena chemopreventive putative.
Dehydroepiandrolone: ʻO Dehydroepiandrolone ( DHEA ), ʻike ʻia ʻo androstenolone , kahi endogenous steroid pūnana mua. ʻO ia kekahi o nā steroid e hoʻopuni nei i nā kānaka. Hana ʻia ka DHEA ma nā gland adrenal, nā gonad, a me ka lolo. Hana ia ma ke ʻano he metabolic intermediate i ka biosynthesis o ka androgen a me ka estrogen sex steroid i loko o nā gonad a me nā kino like ʻole. Eia nō naʻe, he ʻano like ʻole kā DHEA o nā hopena biological i loko o kāna pono ponoʻī, e hoʻopaʻa ana i nā lālani o nā ʻenekini nuklea a me nā ʻili pūnaewele, a ke hana nei ma ke ʻano he neurosteroid a me ka modulator o nā mea loaʻa nā neurotrophic factor.
ʻO Desmethoxyyangonin: ʻO Desmethoxyyangonin a i ʻole 5,6-dehydrokavain kekahi o nā kavalactones nui ʻeono i loaʻa i ka Piper methysticum (kava) mea kanu.
ʻO Desmethoxyyangonin: ʻO Desmethoxyyangonin a i ʻole 5,6-dehydrokavain kekahi o nā kavalactones nui ʻeono i loaʻa i ka Piper methysticum (kava) mea kanu.
Dehydronorketamine: ʻO Dehydronorketamine ( DHNK ), a i ʻole 5,6-dehydronorketamine , kahi metabolite liʻiliʻi o ka ketamine i hana ʻia e ka dehydrogenation o kāna metabolite norketamine. ʻOiai manaʻo mua ʻole ʻia e hana ʻole, ua ʻike ʻia ka DHNK e hana ma ke ʻano he modulator allosteric maikaʻi a koho ʻia o ka α 7 -nicotinic acetylcholine receptor ( IC 50 = 55 nM). No kēia kumu, like me ka hydroxynorketamine (HNK), ua kuhi ʻia he mana ko DHNK e hana i nā hopena antidepressant wikiwiki. Eia nō naʻe, ʻokoʻa ka ketamine, norketamine, a me HNK, ʻike ʻole ʻia ka hana ʻole o DHNK i ka hōʻike ʻauʻau ʻauʻau (FST) i nā ʻiole ma nā kaha a i 50 mg / kg. Hana ʻole ʻo DHNK ma ka receptor α 3 β 4 -nicotinic acetylcholine (IC 50 > 100 μM) a hana palupalu wale i ka receptor NMDA (K i = 38.95 μM no ( S ) - (+) - DHNK). Hiki ke ʻike ʻia he 7-10 mau lā ma hope o kahi mahele haʻahaʻa o ka ketamine, a ma muli o kēia, pono i nā hoʻokolohua ʻike lāʻau.
5,6-Dichloro-1-beta-D-ribofuranosylbenzimidazole: 5,6-Dichloro-1-β- d -ribofuranosylbenzimidazole (DRB) kahi hui kemika e kāohi i ka elongation transcription na RNA Polymerase II. Pili ka ʻike i ka DRB ma muli o ka DRB ʻike ʻia i ke kumu (DSIF), ke kumu elongation maikaʻi (NELF), a me ka helu elongation transcription maikaʻi b (P-TEFb). ʻO DRB kahi analog nukleoside a pāpā pū kekahi i kekahi kinases protein.
Dehydroepiandrolone: ʻO Dehydroepiandrolone ( DHEA ), ʻike ʻia ʻo androstenolone , kahi endogenous steroid pūnana mua. ʻO ia kekahi o nā steroid e hoʻopuni nei i nā kānaka. Hana ʻia ka DHEA ma nā gland adrenal, nā gonad, a me ka lolo. Hana ia ma ke ʻano he metabolic intermediate i ka biosynthesis o ka androgen a me ka estrogen sex steroid i loko o nā gonad a me nā kino like ʻole. Eia nō naʻe, he ʻano like ʻole kā DHEA o nā hopena biological i loko o kāna pono ponoʻī, e hoʻopaʻa ana i nā lālani o nā ʻenekini nuklea a me nā ʻili pūnaewele, a ke hana nei ma ke ʻano he neurosteroid a me ka modulator o nā mea loaʻa nā neurotrophic factor.
5,6-Dihydro-5 (α-thyminyl) thymine: ʻO 5,6-Dihydro-5 (α-thyminyl) koumine kahi DNA pyrimidine dimer photoproduct i hana ʻia ke hōʻike ʻia ʻo DNA i nā spore bacteria i ke kukui ultraviolet.
Dihydrouracil dehydrogenase (NAD +): I ka enzymology, he dihydrouracil dehydrogenase (NAD +) (EC 1.3.1.1 ) kahi enzyme e catalyzed i ka hopena kemika 5,6-dihydrouracil + NAD + uracil + NADH + H +
ʻO Dihydropyrimidinase: I ka enzymology, he dihydropyrimidinase (EC 3.5.2.2 ) kahi enzyme e catalyze i ka hopena kemika 5,6-dihydrouracil + H 2 ʻO 3-ureidopropanoate
ʻO Dihydrouracil: ʻO Dihydrouracil kahi mea waena i ka catabolism o uracil.
Dihydropyrimidine dehydrogenase (NADP +): I ka enzymology, he dihydropyrimidine dehydrogenase (NADP +) (EC 1.3.1.2 ) kahi enzyme e catalyze i ka hopena kemika 5,6-dihydrouracil + NADP + uracil + NADPH + H +
Dihydrouracil oxidase: I ka enzymology, he dihydrouracil oxidase (EC 1.3.3.7 ) kahi enzyme e catalyzed i ka hopena kemika 5,6-dihydrouracil + O 2 uracil + H 2 O 2
ʻO Dihydrouridine: ʻO Dihydrouridine (hoʻopōkole ʻia e like me D , DHU , a i ʻole UH 2 ) he pyrimidine nucleoside ka hopena o ka hoʻohui ʻana i ʻelua mau ʻoma hydrogen i kahi uridine, e hana ana i ke apo pyrimidine piha piha me ka ʻole o nā paʻa pālua i koe. Loaʻa ʻo D i nā mole tRNA a me rRNA ma ke ʻano he nucleoside; ʻo ka nucleobase kūlike he 5,6-dihydrouracil.
5,6-dihydroxy-3-methyl-2-oxo-1,2,5,6-tetrahydroquinoline dehydrogenase: I loko o ka enzymology, kahi 5,6-dihydroxy-3-methyl-2-oxo-1,2,5,6-tetrahydroquinoline dehydrogenase (EC 1.3.1.65 ) kahi enzyme e catalyze i ka hopena kemika 5,6-dihydroxy-3-methyl-2-oxo-1,2,5,6-tetrahydroquinoline + NAD + 5,6-dihydroxy-3-methyl-2-oxo-1,2-dihydroquinoline + NADH + H +
5,6-dihydroxy-3-methyl-2-oxo-1,2,5,6-tetrahydroquinoline dehydrogenase: I loko o ka enzymology, kahi 5,6-dihydroxy-3-methyl-2-oxo-1,2,5,6-tetrahydroquinoline dehydrogenase (EC 1.3.1.65 ) kahi enzyme e catalyze i ka hopena kemika 5,6-dihydroxy-3-methyl-2-oxo-1,2,5,6-tetrahydroquinoline + NAD + 5,6-dihydroxy-3-methyl-2-oxo-1,2-dihydroquinoline + NADH + H +
5,6-Dihydroxycytosine: 5,6-Dihydroxycytosine hiki ke hana ʻia mai ka mālama ʻana iā DNA me ka osmium tetroxide.
Melanin: ʻO Melanin kahi manawa ākea no kahi hui o nā pigment kūlohelohe i loaʻa i ka hapa nui o nā meaola. Hana ʻia ʻo Melanin ma o ke kaʻina hana kemika multistage i ʻike ʻia ma ke ʻano he melanogenesis, kahi e ukali ʻia ai ka oxidation o ka amino acid tyrosine e ka polymerization. Hana ʻia nā melanin pigment i kahi hui kūikawā o nā hunaola i ʻike ʻia he melanocytes.
ʻO Dimethylbenzimidazole: 5,6-Dimethylbenzimidazole kahi kūpuna benzimidazole kūlohelohe. ʻO ia kahi ʻāpana o ka wikamina B 12 kahi i lawelawe ʻia ma ke ʻano he ligand no ka ʻohā cobalt.
5,6-dimethylbenzimidazole synthase: 5,6-dimethylbenzimidazole synthase (EC 1.14.99.40 , BluB ) kahi enzyme me ka inoa ʻōnaehana FMNH 2 oxidoreductase (5,6-dimethylbenzimidazole e hoʻokumu nei) . Hoʻopili kēia enzyme i ka hopena kemika i lalo FMNH 2 + NADH + H + + O 2 5,6-dimethylbenzimidazole + D-erythrose 4-phosphate + NAD + + huahana ʻē aʻe
MDAI: ʻO MDAI ( 5,6-methylenedioxy-2-aminoindane ) kahi lāʻau i hoʻomohala ʻia i nā makahiki 1990 e kahi kime i alakaʻi ʻia e David E. Nichols ma ke Kulanui ʻo Purdue. Hana ia ma ke ʻano he neurotoxic non-selective a me ke koho koho serotonin (SSRA) i vitro a hana i nā hopena entactogen i nā kānaka.
MDMAI: 5,6-Methylenedioxy- N -methyl-2-aminoindane ( MDMAI ), he lāʻau i hoʻomohala ʻia i nā makahiki 1990 e kahi hui i alakaʻi ʻia e David E. Nichols ma ke Kulanui ʻo Purdue. Hana ia ma ke ʻano neurotrokika non-neurotoxic a me ka mea koho nui loa (SSRA) i nā holoholona a me kahi entactogen putative i loko o nā kānaka.
ʻO Violaxanthin: ʻO Violaxanthin kahi pigment xanthophyll kūlohelohe me kahi kala ʻalani i loaʻa i nā mea kanu like ʻole, me nā pansies. Hoʻokomo ʻia ia mai zeaxanthin e epoxidation. Hoʻohana ʻia ia ma ke ʻano he meaʻai waihoʻoluʻu ma lalo o ka helu E E161e a me INS helu 161e. ʻAʻole ʻae ʻia ka kala no ka hoʻohana ʻana i ka meaʻai ma EU a i ʻAmelika Hui Pū ʻIa, akā ʻae ʻia ma Australia a me New Zealand.
Cholesterol-5,6-oxide hydrolase: ʻO Cholesterol-5,6-oxide hydrolase (EC 3.3.2.11 , kolesterol -epoxide hydrolase , ChEH ) kahi enzyme me ka inoa ʻōnaehana 5,6alpha-epoxy-5alpha-cholestan-3beta-ol hydrolase . Hoʻopili kēia enzyme i ka hopena kemika i lalo (1) 5,6alpha-epoxy-5alpha-cholestan-3beta-ol + H 2 O 5alpha-cholestane-3beta, 5alpha, 6beta-triol (2) 5,6beta-epoxy-5beta-cholestan-3beta-ol + H 2 O 5alpha-cholestane-3beta, 5alpha, 6beta-triol
Tricetin: ʻO Tricetin kahi flavone, kahi ʻano flavonoid. He aglycone laha ʻole ia i loaʻa i ka pollen o nā lālā o ka Myrtaceae, ka ʻohana Leptospermoideae, e like me Eucalyptus globulus . Hōʻike kēia mea hoʻohui i nā hopena anticancer ma ka umauma adenocarcinoma MCF-7 pūnaewele.
Tricetin: ʻO Tricetin kahi flavone, kahi ʻano flavonoid. He aglycone laha ʻole ia i loaʻa i ka pollen o nā lālā o ka Myrtaceae, ka ʻohana Leptospermoideae, e like me Eucalyptus globulus . Hōʻike kēia mea hoʻohui i nā hopena anticancer ma ka umauma adenocarcinoma MCF-7 pūnaewele.
Orobol: ʻO Orobol kekahi o nā isoflavones i ʻike ʻia. Hiki ke hoʻokaʻawale iā Aspergillus niger a i ʻole Streptomyces neyagawaensis . He mea kāohi i ka Phosphoinositide 3-kinase.
Isorhamnetin: ʻO Isorhamnetin kahi O-methylated flavon-ol mai ka papa o nā flavonoids. ʻO kahi kumuwaiwai meaʻai maʻamau o kēia 3'-methoxylated derivative o quercetin a me kāna glucoside conjugates he pungent melemele a ʻulaʻula onions, kahi o ia mea he liʻiliʻi pigment, quercetin-3,4'-diglucoside a me quercetin-4'-glucoside a me ka aglycone ʻo ka quercetin nā pigment nui. ʻO ka peʻa, ka ʻaila ʻoliva, ka waina a me ka wai kōmato ka waiwai i ka isorhamnetin. ʻO nā kumuwaiwai ʻē aʻe e pili ana i ka mea ʻala, lāʻau lāʻau lapaʻau a me ka psychoactive Mexican tarragon (Tagetes lucida) , i wehewehe ʻia e like me ka hōʻiliʻili ʻana i ka isorhamnetin a me kāna derivate 7-O-glucoside. ʻO Nopal kahi kumu maikaʻi o ka isorhamnetin, i hiki ke huki ʻia e ka unuhi wai supercritical i kōkua ʻia e nā enzyme.
Luteolin: ʻO Luteolin kahi flavone, kahi ʻano flavonoid, me ka helehelena crystalline melemele.
Centaureidin: ʻO Centaureidin kahi flavonol O-methylated. Hiki ke hoʻokaʻawale ʻia mai Tanacetum microphyllum , Achillea millefolium , Brickellia veronicaefolia , Bidens pilosa a me Polymnia fruticosa .
ʻO Juglanin: ʻO Juglanin kahi flavonol i loaʻa ma Polygonum aviculare .
5,7,4'-Trimethoxyflavan: 5,7,4'-Trimethoxyflavan kahi flavan, kahi ʻano flavonoid. Hiki ke loaʻa iā Xanthorrhoea preissii .
Apigenin: ʻO Apigenin (4 ', 5,7-trihydroxyflavone), loaʻa i nā mea kanu he nui, he huahana kūlohelohe ia no ka papa flavone ʻo ia ka aglycone o kekahi mau glycosides kūlohelohe. ʻO ia kahi paʻa crystalline melemele i hoʻohana ʻia e kala i ka hulu hipa.
5,7,4'-Trimethoxyflavan: 5,7,4'-Trimethoxyflavan kahi flavan, kahi ʻano flavonoid. Hiki ke loaʻa iā Xanthorrhoea preissii .
Kolamu: ʻO Columnidin kahi pigment ʻulaʻula ʻalani, no nā 3-deoxyanthocyanidins i loaʻa i nā ʻulaʻula komohana-hemisphere gesneriad e like me episcias, columneas, sarmientas, a me sinningias.
ʻO Norwogonin: ʻO Norwogonin , a i ʻike ʻia hoʻi me 5,7,8-trihydroxyflavone ( 5,7,8-THF ), he flavone, kahi kūlohelohe maoli e like me flavonoid-like pūhui kemika i loaʻa ma Scutellaria baicalensis . Ua ʻike ʻia e hana ma ke ʻano he agonist o ka TrkB, ka reseptor hōʻailona nui o ka neurotrophic factor i loaʻa i ka lolo (BDNF), a me he mea lā he ʻano like ka hana e pili ana i ka pili a pili pono akā 7 kaulana loa. , 8-dihydroxyflavone (7,8-DHF).
Isoscutellarein: ʻO Isoscutellarein kahi flavone i loaʻa ma Cupuaçu a i ka atewort Marchantia berteroana .
ʻO Norwogonin: ʻO Norwogonin , a i ʻike ʻia hoʻi me 5,7,8-trihydroxyflavone ( 5,7,8-THF ), he flavone, kahi kūlohelohe maoli e like me flavonoid-like pūhui kemika i loaʻa ma Scutellaria baicalensis . Ua ʻike ʻia e hana ma ke ʻano he agonist o ka TrkB, ka reseptor hōʻailona nui o ka neurotrophic factor i loaʻa i ka lolo (BDNF), a me he mea lā he ʻano like ka hana e pili ana i ka pili a pili pono akā 7 kaulana loa. , 8-dihydroxyflavone (7,8-DHF).
Isoscutellarein: ʻO Isoscutellarein kahi flavone i loaʻa ma Cupuaçu a i ka atewort Marchantia berteroana .
ʻO Norwogonin: ʻO Norwogonin , a i ʻike ʻia hoʻi me 5,7,8-trihydroxyflavone ( 5,7,8-THF ), he flavone, kahi kūlohelohe maoli e like me flavonoid-like pūhui kemika i loaʻa ma Scutellaria baicalensis . Ua ʻike ʻia e hana ma ke ʻano he agonist o ka TrkB, ka reseptor hōʻailona nui o ka neurotrophic factor i loaʻa i ka lolo (BDNF), a me he mea lā he ʻano like ka hana e pili ana i ka pili a pili pono akā 7 kaulana loa. , 8-dihydroxyflavone (7,8-DHF).
ʻO Norwogonin: ʻO Norwogonin , a i ʻike ʻia hoʻi me 5,7,8-trihydroxyflavone ( 5,7,8-THF ), he flavone, kahi kūlohelohe maoli e like me flavonoid-like pūhui kemika i loaʻa ma Scutellaria baicalensis . Ua ʻike ʻia e hana ma ke ʻano he agonist o ka TrkB, ka reseptor hōʻailona nui o ka neurotrophic factor i loaʻa i ka lolo (BDNF), a me he mea lā he ʻano like ka hana e pili ana i ka pili a pili pono akā 7 kaulana loa. , 8-dihydroxyflavone (7,8-DHF).
5,7-Dihydroxytr Egyptamine: 5,7-Dihydroxytr Egyptamine ( 5,7-DHT ) kahi neurotoxin i manaʻo ʻia e hoʻohana ʻia i ka ʻepekema noiʻi e hoʻoliʻiliʻi i nā concentrations o serotonin i ka lolo. ʻAʻole maopopo maikaʻi ke ʻano o ke kumu ma hope o kēia hopena, akā manaʻo ka hapa nui e luku wale ia i nā neurons serotonergic, ma ke ʻano like e hoʻohana ʻia ai ka 6-hydroxydopamine (6-OHDA) e pepehi i nā hunaola dopaminergic ʻO ka mea i ʻike ʻia ʻaʻole koho ʻia kēia pūhui i ka hoʻopau ʻana i ka ʻike serotonin, akā hoʻopau pū kekahi i ka norepinephrine. No ka hoʻopau pono ʻana i nā hale kūʻai serotonin, lawelawe pinepine ʻia ia me ka desmethylimipramine (desipramine) [3], kahi e kāohi i ka mea lawe norepinephrine.
5,7-Dichlorokynurenic acid: 5,7-Dichlorokynurenic acid ( DCKA ) kahi mea koho n antagonist receptor NMDA e hana ana ma ka pūnaewele glycine o ka complex receptor NMDA.
Acacetin: ʻO Acacetin kahi 4'-O-methylated flavone o ka makua hui Apigenin, i loaʻa ma Robinia pseudoacacia , ʻo Turnera diffusa (damiana), e hōʻike ana i ke kaohi ʻana o ka aromatase, Betula pendula , a me ka fern Asplenium normale .
Eupatilin: ʻO Eupatilin (5,7-Dihydroxy-3 ', 4', 6-trimethoxyflavone) kahi flavone O-methylated, kahi ʻano flavonoids. Hiki ke loaʻa ma Artemisia asiatica (Asteraceae).
Ermanin: ʻO Ermanin kahi flavonol O -methylated . Ua kaʻawale ia mai Tanacetum microphyllum .
Santin (flavonol): ʻO Santin kahi flavonol O-methylated. Ua kaʻawale ia mai Tanacetum microphyllum .
Ermanin: ʻO Ermanin kahi flavonol O -methylated . Ua kaʻawale ia mai Tanacetum microphyllum .
ʻO Biochanin A: ʻO Biochanin A kahi O -methylated isoflavone . He hui kūlohelohe maoli ia i ka papa o nā phytochemical i ʻike ʻia ʻo flavonoids. Hiki ke loaʻa ʻo Biochanin A i ka ʻulaʻula i ka soy, i nā ʻōpuʻu alfalfa, i nā pī, nā moa a me nā hua ʻē aʻe.
ʻO Wogonin: ʻO Wogonin kahi flavone O-methylated, kahi hui kemika like flavonoid i loaʻa ma Scutellaria baicalensis .